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How to Read a Peptide Certificate of Analysis (COA)

A certificate of analysis (COA) is the lab report that shows what is actually in a vial. Knowing how to read one is the single best way to tell a reputable research peptide supplier from a bad one.

HPLC PURITY

High-performance liquid chromatography separates the contents of a sample. The result is shown as a chromatogram with peaks; purity is the main peak’s area as a percentage of all peaks. Research-grade peptides should test at ≥98–99%. Every PrimeSyns compound is verified at ≥99%.

MASS SPECTROMETRY

HPLC tells you how pure a sample is, but not what it is. Mass spec confirms identity by measuring molecular weight — the observed mass should match the peptide’s theoretical mass closely.

RED FLAGS

  • No COA available, or only on request
  • A COA with no lot number, or a lot that does not match your vial
  • Purity claims with no chromatogram
  • Identical-looking reports across different compounds

SEE OURS

Lab results for PrimeSyns products are published on our Lab Results page.

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≥99% HPLC-verified purity · Free US shipping on $99+

This guide is for informational and laboratory research purposes only. PrimeSyns products are not intended for human consumption, and nothing here is medical advice.

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